Zoe the Thorny Devil

Zoe first appears observing Jackie scaring a little girl before the show on security videos, amusing her enough to say that it will be fun when Maddie is seen. Frank suggests waking Maddie up, but Zoe prefers that she see things for herself. The trio are then taken away uncomfortably for the show about to begin. At the time of the show, Zoe appears under Chaz's hat, referred to as a disgusting thing and then is taken along with Nigel and Frank as Maddie is about to be introduced for the first time.

After dark, Zoe and the arachnids notice that Maddie has been unhappy since she was called a monster by the mob. When Jackie asks for Maddie's first impression, the three nod to the crocodile that it's not going well, prompting Jackie to try to cheer Maddie up by bringing up the qualities of each, like Zoe's intelligence which proceeds to skillfully lower the lamp from the vivarium with just a small pebble. Maddie doesn't feel any better though, as she would like to be loved like the Pretty Boy who Zoe just finds disgusting just by looking at him through the cameras. Zoe then listened to a story about Jackie on the Outback before going to sleep.

The following days, Zoe continues to scare visitors to the zoo and at one point received a bucket full of popcorn to the face. After Jackie is wrongly accused of wanting to attack Chazzie and is being taken away, Maddie tries to get out of the vivarium by bumping into it until Zoe tells her to calm down and then leaves the reptile house only to witness to her great sadness Jackie's expulsion from the zoo, exchanging one last look with her mother figure. After that they were saddened because of Jackie's loss.

Following this event, Maddie cheers up, refuses telling a story about the Outback and convinces her three friends that it is time for them to give up their miserable life as zoo freaks and go to the Outback where they can reunite with their families. As the four animals manage to cross the zoo without having arrived, Maddie declares that she is sure they will get there, but Zoe advises her not to say that when a noise calls out to them. They notice Pretty Boy deliberately making a noise so that the runaways get caught. The obnoxious koala then accidentally gets stung by Nigel and falls to the other side of the wall, followed by the four animals whose landing is cushioned by Maddie.

Dropped on the shore by Jacinta, Zoe remarks that the humans will kill them when they see them before Pretty Boy dares to use her as a comb and obnoxiously leaves the gang, causing Zoe to call him a jerk. As they sneak through the alleys hiding in the garbage with Zoe forced to share a Chinese lunch box with the two arachnids, the gang find themselves surrounded by an angry mob chasing Pretty Boy.

With no way out, the animals try to remember the U.S.S. password as humans approach them hostilely. The moment Maddie says the password, the humans cover the animals in a suit and apparently begin to stomp on them only to discover that they are missing, leaving only the manhole cover they were standing on.

Now in the sewers, the gang is approached by their saviors, redback spiders whose Frank tries to flirt with the female boss, only for Zoe to slap him in exasperation and then when Nigel asks Pretty Boy if he can wipe his fur, Zoe tells him to stop before the gang is carried away by the water channel to the treatment plant. At first frightened, Zoe and the other fugitives quickly take pleasure in the aquatic descent, the thorny devil having fun surfing on the pipes and the walls before being expelled through the ventilation duct onto a window washer platform.

The gang goes down to an elementary school where they meet two cane toads that Maddie releases despite Zoe being wary of their toxicity because of the posters on the walls. The toads then inform them that one of the buses is heading for the Outback. Aside from the brutality of the children, the gang manages to get on a bus but Zoe realizes it's not the right one as they start to move. Fortunately, the horned devil has the idea of using a skateboard and a flag to reach the roof of the other bus.

Later as the bus goes deeper into nature, Zoe takes the opportunity to feed on the bees passing near her. When Maddie claims that they will all be happy in the Outback with their families, Zoe admits her skepticism about it since neither of them have ever had one, not even knowing what it really is until Maddie explains that they're the ones who love them exactly the way they are and then hugs them.

Their pleasant moment is brutally interrupted by Chaz and Chazzie chasing them in their jeep, forcing the fleeing group to hide inside the bus where they are almost attacked by the frightened children. A little girl unexpectedly helps them escape, realizing that they just want to find a place to live.

After falling off the cliff, Zoe witnesses an argument between Maddie and Pretty Boy more heinous than ever before Chaz accidentally runs into them, trapping Maddie. Zoe, Frank and Nigel try to charge the human but fall into a crevasse they hadn't seen before being blocked by Chaz's hat. Against all odds, Pretty Boy uses the password to summon three Tasmanian devils who push Chaz back and free the trio by tearing the hat to pieces, allowing the journey to resume.

Successively guided by other members of the U.S.S. through the Australian wilderness for three weeks, the band climbs not far from Ayers Rock where Zoe asks Maddie to sing her mother's lullaby then falls asleep. The next day, Pretty Boy separates from the group after finding a koala tree and again using Zoe as a comb and toothpick.

At dusk, the four friends finally reach the Jackie Stories Mountains and meet other members of their respective species. Unfortunately, they are captured by Chaz accompanied by bikers, although Maddie is freed by a remorseful Chazzie. The next day, Maddie and Pretty Boy come to their friends' rescue in a fire truck while taking on the bikers.

"You're my family!" - Maddie's touching declaration that deeply affects Zoe

During the assault, Maddie admits to Zoe, Frank and Nigel that she considers them her family before Zoe comes up with the idea of making Nigel scream by making him believe he was turning beige so that his shriek would break the unbreakable glass of their cage. Once again reunited, the gang flees towards the canyon in a motorcycle sidecar, still being chased by the humans.

Following the sudden ambush of the Outback animals against the bikers, the gang find themselves with Chaz and Chazzie on the firefighter's ladder holding onto rocks like a seesaw above the void but survive by helping each other in the end. Chaz then made peace with the animals for saving his son. Definitely free, Maddie, Zoe, Frank, Nigel and Pretty Boy are acclaimed as heroes by the animals of the Outback while being reunited with Jackie and finally settle in the Outback.